This shop has been compensated by Inmar, Inc. and Ortho Dermatologics. I am working with the makers of DUOBRII® (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, in 2021. All opinions are mine alone. #ad #AskForDUOBRII #DUOBRII

If you’ve been following my journey with finding the right psoriasis medication, then you know that I talked to my pharmacist here and I have just been waiting to talk to my dermatologist and oncologist about using DUOBRII Lotion from Ortho Dermatologics as an option for treating my plaque psoriasis.

Quick recap: I’m talking to my oncologist because in addition to having psoriasis, I am also a breast cancer survivor. And right now I am undergoing hormone therapy treatment. As always before starting any new medication, you want to make sure to let your doctors know which medication you’ll be starting.

woman with blue top and grey robe holding psoriasis medication-psoriasis-awareness-sabrina-skiles

I am happy to say that I got the all clear from my oncologist. The nurse asked if I needed to schedule a televisit to ask her a few of the questions I had. And I said it wasn’t necessary as it was just as simple as letting her know the name of the medication, DUOBRII Lotion. She wrote that down. And she also asked what the main ingredients were in the medication.

I said halobetasol propionate, which is a strong anti-inflammatory agent that works to clear plaques and a retinoid (tazarotene), a vitamin A derivative which helps extend the clearing process even after stopping treatment.

As I was pouring my morning coffee, I got a call back less than an hour later that said my doctor gave me the go ahead for starting this medication!

Also, I’m so happy to say that I heard back from my dermatologist as well and she said DUOBRII Lotion sounds like a great option for me! There wasn’t a need for a televisit from her either as I just saw her about three months ago. I haven’t had any disease progression or new psoriasis flare-ups, just the stubborn plaques on my knees, elbows and scalp. She suggested going through a specialty pharmacy as they can mail it to you — yay for not having to go into the drug store during COVID! And she mentioned some local pharmacies don’t apply a coupon on their end so it can get rather expensive.

Sabrina in September 2020 with clear psoriasis plaques on her left knee

Why I Like DUOBRII Lotion as an option for me:

  • DUOBRII Lotion combines two well-known ingredients into a single, first-of-its-kind topical treatment
  • DUOBRII Lotion is made of two well-known ingredients that provide benefits being together in one lotion while helping to reduce the side effects of the other
  • DUOBRII Lotion is not a pill or an injection, it’s a once-daily lotion
  • Lasting clearance from plaque psoriasis may be possible with DUOBRII Lotion
  • Cost: Most eligible commercially insured patients will pay as little as a $25 co-pay. For eligible patients whose commercial insurance does not cover DUOBRII Lotion, patients will pay as little as a $65 co-pay
woman with blue top and grey robe holding psoriasis medication-psoriasis-awareness-sabrina-skiles

Now that I have talked to both my doctors I feel comfortable knowing that DUOBRII Lotion is a great option for treating my psoriasis. I hope this has been helpful for you!

Whether it’s scheduling a televisit to discuss if DUOBRII Lotion is right for you or seeing your dermatologist in person is better, just know that you have options when it comes to finding the right psoriasis medication for you. Remember, DUOBRII Lotion should not be used during pregnancy.

Have you talked to your dermatologist about how DUOBRII Lotion can fit into your life? I would love to hear from you!

Don’t forget to check out my first post about researching why DUOBRII Lotion is right for me and the second part about the three phone calls I had to make to my healthcare team here.

woman with blue top and grey robe holding psoriasis medication-psoriasis-awareness-sabrina-skiles

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy. 

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.

What should I avoid during treatment with DUOBRII?

  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.

DUOBRII may cause side effects, including:

  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit

Please click here for full Prescribing Information, including Patient Information. 




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