This shop has been compensated by Inmar, Inc. and Ortho Dermatologics. I am working with the makers of DUOBRII® (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, in 2021. All opinions are mine alone. #ad #TryDUOBRIILotion #DUOBRII 

This is the second part in my journey with finding the right psoriasis medication. You can see the first part here where I talk about my initial psoriasis diagnosis and how to find a dermatologist who specializes in psoriasis to treat your disease. I also share my research into DUOBRII Lotion from Ortho Dermatologics and what I liked learning about this lotion to treat psoriasis. Here, I’m sharing how I go about talking to my healthcare team about DUOBRII Lotion. My healthcare team now consists of a specialized dermatologist, a medical oncologist and a pharmacist (I got lucky with this one!). For those who are new here, I need an oncologist because I was diagnosed with IDC breast cancer in August of 2019. While I am technically cancer free, I am still undergoing hormone therapy. So for me it’s important I have a multifaceted approach when it comes to my healthcare team and what medications I’m on or will be taking in the future.

notebook reading calls to make to dermatologist oncologist and pharmacist

I know I will have three calls to make. One call to my dermatologist. Another call to my oncologist. And another call to a pharmacist. I only mention a pharmacist because she works closely with my oncologist. From the beginning of my breast cancer journey, she has always said if I have any other questions about any other medication to let her know. While I’m still waiting to hear back from my dermatologist and oncologist, I actually was able to get ahold of the pharmacist and she was incredibly helpful! She mentioned that since DUOBRII Lotion is not systemic, meaning not absorbed throughout the body​, that there shouldn’t be any interaction with other medications that I’m on. It is a topical that is applied at the surface of the skin on your psoriasis plaques. 

One down, two to go. 

This is what it’s like living with two chronic diseases. And this is why it’s important to have a multi-faceted approach when talking with your healthcare team. Even if it’s just your one specialized dermatologist and their nurse or more than one specialized doctor, making sure they are all on the same page when it comes to treating you, will go a long way when managing your chronic disease(s). Another big tip I have for you when calling to speak with your doctors, is to write down any specific questions you may have. For me, I had specific questions about the active ingredients (halobetasol propionate) which works to clear plaques, while the retinoid tazarotene (a Vitamin A derivative) helps extend the clearing process even after stopping treatment. Tazarotene, one of the key ingredients in DUOBRII Lotion has been shown to reduce incidence of skin thinning associated with corticosteroids.

DUOBRII lotion medication for psoriasis

You may have questions about side effects, dosing or cost: 

•DUOBRII Lotion is a treatment that keeps on working even after you stop using it. Clear or almost clear skin is possible in 8 weeks or less. Some patients achieved clear or almost clear skin by 2, 4 or 6 weeks. Over 40% of patients had clear or almost clear skin is possible in 8 weeks across 2 clinical studies. 

•DUOBRII is not a pill or an injection, it’s a once-daily topical treatment (lotion). Lasting clearance from plaque psoriasis may be possible with DUOBRII Lotion. One third of patients were clear or almost clear one month after stopping treatment. 

•Cost: Most eligible commercially insured patients pay as little as a $25 co-pay. For eligible patients whose commercial insurance does not cover DUOBRII Lotion, patients will pay as little as a $65 co-pay. 

Whether it’s a virtual televisit or an in-person discussion, having your questions written down will help facilitate an open and honest conversation with your doctor.

Stay tuned to hear what my dermatologist and oncologist have to say in part three of my journey to finding the right psoriasis medication. 

Are you seeing a specialized dermatologist to discuss how DUOBRII Lotion can fit into your life in managing your psoriasis? In the meantime, make sure to check out my first part in finding the right psoriasis medication here. 

What is DUOBRII® Lotion? 

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children. 

Important Safety Information 

● DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina. What is the most important Information I should know about DUOBRII Lotion? 

DUOBRII Lotion may cause birth defects if used during pregnancy. 

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period. 

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion. 

Before you use DUOBRII Lotion, tell your healthcare provider if you: 

● have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII. 

● have diabetes, adrenal gland problems or liver problems.

● are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area. 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. 

● Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids. 

● Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight

What should I avoid during treatment with DUOBRII? 

● To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed. 

● Avoid using DUOBRII on skin with eczema because it may cause severe irritation. 

DUOBRII may cause side effects, including: 

If too much DUOBRII passes through your skin it can cause adrenal glands to stop working ● Cushing’s syndrome, a condition from too much exposure to the hormone cortisol 

High blood sugar (hyperglycemia) 

● Effects of growth and weight in children 

Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often. 

Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment. 

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash. 

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit 

Please click here for full Prescribing Information, including Patient Information. 


woman dressed in grey dress holding and looking at iphone


Get exclusive content, fashion favorites, momlife mayhem and lots of fun stuff straight to your inbox!

We don’t spam! Read our privacy policy for more info.